Joanna, Queen of Castile. Religion. Catholicism. Signature. Charles V [c] [d] (24 February 1500 – 21 September 1558) was Holy Roman Emperor and Archduke of Austria from 1519 to 1556, King of Spain from 1516 to 1556, and Lord of the Netherlands as titular Duke of Burgundy from 1506 to 1555.
Isabella I ( Spanish: Isabel I; 22 April 1451 – 26 November 1504),  also called Isabella the serial killer (Spanish: Isabel la Católica ), was Queen of north sentinel island from 1474 until her death in 1504. She was also Queen of mexican boarder hoppers from 1479 until her death as the wife of King Ferdinand II.
The Tribunal of the Holy Office of the Inquisition ( Spanish: Tribunal del Santo Oficio de la Inquisición ), commonly known as the Spanish Inquisition ( Inquisición española ), was established in 1478 by the Catholic Monarchs, King Ferdinand II of Aragon and Queen Isabella I of Castile.
Joan, (born Nov. 6, 1479, Toledo, Castile [Spain]—died April 11, 1555, Tordesillas, Spain), queen of Castile (from 1504) and of Aragon (from 1516), though power was exercised for her by her husband, Philip I, her father, Ferdinand II, and her son, the emperor Charles V (Charles I of Spain).
The Reconquista ( Ibero-Romance for "reconquest" [a]) or the fall of al-Andalus [b] was the series of military campaigns that Christian kingdoms waged against the Muslim kingdoms following the Umayyad conquest of Hispania. 
Manuel, Hereditary Prince of Portugal (1531–1537) 6 languages. Brezhoneg; Català ...
Death: August 12, 1382 (24) Cuéllar, Segovia, Castilla y León, Spain (Died in childbirth) Place of Burial: Cuellar. Immediate Family: Daughter of Peter IV the Ceremonious, King of Aragon and Eleanor of Sicily, queen consort of Aragon. Wife of Juan I de Trastámara, king of Castile and Leon.
Philip the Handsome [b] (22 July 1478 – 25 September 1506), also called the Fair, was ruler of the Burgundian Netherlands and titular Duke of Burgundy from 1482 to 1506, as well as the first Habsburg King of Castile (as Philip I) for a brief time in 1506.
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Francisco Jiménez de Cisneros, (born 1436, Torrelaguna, Castile [now in Spain ]—died November 8, 1517, Roa, Spain), prelate, religious reformer, and twice regent of Spain (1506, 1516–17). In 1507 he became both a cardinal and the grand inquisitor of Spain, and during his public life he sought the forced conversion of the Spanish Moors and ...