SARS-CoV-2 is the seventh known coronavirus to infect people, after 229E, NL63, OC43, HKU1, MERS-CoV, and the original SARS-CoV.  Like the SARS-related coronavirus implicated in the 2003 SARS outbreak, SARS‑CoV‑2 is a member of the subgenus Sarbecovirus ( beta-CoV lineage B).
SARS-CoV-2 has consistently mutated over the course of the pandemic, resulting in variants that are different from the original SARS-CoV-2 virus. Throughout the COVID-19 pandemic, many variants of SARS-CoV-2 have been found in the United States and globally .
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory...
This overview describes current information on the types of tests used to detect SARS-CoV-2 infection and their intended uses. This information is intended for use by healthcare providers, public health professionals, and those organizing and implementing testing in non-healthcare settings.
SARS-CoV-2 has been shown to infect cells in two ways: entry through endocytic mechanisms or through fusion of the viral envelope with the host cell plasma membrane . In both cases, the spike protein subunits, S1 and S2, mediate attachment and entry by binding with the cell surface protein, angiotensin-converting enzyme 2 (ACE2).
ICTV announced “severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)” as the name of the new virus on 11 February 2020. This name was chosen because the virus is genetically related to the coronavirus responsible for the SARS outbreak of 2003. While related, the two viruses are different.
While monitoring the circulation of SARS-CoV-2 globally, it also remains essential to monitor their spread in animal populations and chronically infected individuals, which are crucial aspects of the global strategy to reduce the occurrence of mutations that have negative public health implications.
SARS-CoV-2 is genetically similar to SARS-CoV-1, but characteristics of SARS-CoV-2—eg, structural differences in its surface proteins and viral load kinetics—may help explain its enhanced rate of transmission
1. What are variants of SARS-COV-2, the virus that causes COVID-19? 2. What is the difference between variants under monitoring, variants of interest, and variants of concern? 3. What can I do to protect myself from SARS-CoV-2 variants? 4. How can we stop new variants from emerging? 5. Do COVID-19 vaccines protect against newer virus variant?
SARS-CoV-2 is a positive-sense single-stranded RNA virus. It is contagious in humans and is the cause of the coronavirus disease 2019 (COVID-19). Featured The highly mutated SARS-CoV-2 variant...