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Updated. Dec. 13, 2022, 12:57 p.m. ET. Reports of “Paxlovid rebound” popped up in the spring of 2022, as some people who had taken the antiviral medication experienced a recurrence of Covid ...
What is Paxlovid rebound? The CDC defines Paxlovid rebound as when a patient who, after receiving a full five-day course of treatment, either has a reemergence of COVID symptoms or tests positive...
Paxlovid rebound is a term used to describe when a person experiences worsening of COVID symptoms after initially getting better after taking Paxlovid. But COVID rebound isn’t a side effect of Paxlovid. It can happen to people taking any COVID treatment, as well as to people who received no treatment at all.
What is the rebound effect of Paxlovid? There have been reports of a “rebound” of COVID-19 symptoms in some people within 2 to 8 days after completing the five-day course of Paxlovid; in those cases, some have tested positive again but have no symptoms; others have a recurrence of symptoms.
While there’s no evidence that Paxlovid rebound is a consequence of the virus developing resistance against the treatment, some scientists believe it is “a matter of time” before this happens.
Less understood about Paxlovid and COVID in general is a person's chance of "rebound" – a phenomenon in which a person recovers from an infection and tests negative, only to redevelop COVID symptoms or test positive within eight days after recovering.
COVID rebound occurs when a person who has COVID-19 tests negative, then within two to eight days has a recurrence of symptoms or a new positive test. This definition comes from the Centers for...