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Obeticholic acid may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: mouth or throat pain. fast, irregular, or pounding heartbeat. rash. dizziness. fainting. swelling of the hands, feet, ankles, or lower legs. joint or muscle pain.

Cholic acid, also known as 3α,7α,12α-trihydroxy-5β-cholan-24-oic acid is a primary bile acid [3] that is insoluble in water (soluble in alcohol and acetic acid ), it is a white crystalline substance. Salts of cholic acid are called cholates.

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ISSUE: The FDA is restricting the use of the liver disease medicine Ocaliva (obeticholic acid) in patients having primary biliary cholangitis (PBC) with advanced cirrhosis of the liver because it...

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ad·dic·tion (ə-dĭk′shən) n. 1. a. A condition involving use of a substance, such as a drug or alcohol, or engagement in a behavior, such as gambling, in which a person ...